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Kombiglyze

Kombiglyze is a prescription medication that contains a combination of two active ingredients, saxagliptin and metformin. It is used to treat type 2 diabetes in adults by helping to control blood sugar levels. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps increase insulin production and decrease glucose production, while metformin helps to decrease glucose production in the liver and improve insulin sensitivity in the body. Kombiglyze is typically taken once or twice daily with food.

Depletion Beneficial Side Effects Recommendation

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Kombiglyze

Depletes

Prolonged use of Kombiglyze can impact 4 essential nutrients.

Vitamin B12

Thiamine Vitamin B1

CoQ10

Folic Acid

Also Affects:

Taurine

Chromium Polynicotinate

Gymnema sylvestre

Alpha Lipoic Acid

Health Impact

Kombiglyze-induced nutrient depletion can lead to a range of health problems

B12-Related Megaloblastic Anemia

B12 Neuropathy & Cognitive Decline

Statin-Related Muscle Pain & Fatigue

Low Mitochondrial Energy & Antioxidant Defense

High Homocysteine & Vascular Risk

Folate-Related Megaloblastic Anemia

Side Effects

Common side effects of Kombiglyze, some of which may be related to nutrient depletion

Review

Get Support

We’ve provided a carefully curated list of vetted, recommended third-party supplements, offering alternative options that meet our high standards for quality, purity, and effectiveness.

Folate

by Pure Encapsulations

Vitamin B12 Methylcobalamin

by Pure Encapsulations

COQ 10 (as Ubiquinone)

by Life Extension

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